Freddy J.K. Toloza, Carlos O. Mendivil
Aldosterone is a key regulator of water and electrolyte metabolism, but recent evidence from multiple lines of research also identifies it as a major player in other chronic disorders, particularly diabetes and the metabolic syndrome. In this review, we summarize rel- evant aspects of aldosterone production, secretion, action, the way aldosterone and the mineralocorticoid receptor may impact energy metabolism, and useful take-home messages concerning mineralocorticoid antagonism in patients with type 2 diabetes mellitus.
Palabras clave: Aldosterone. Electrolyte metabolism. Diabetes. Metabolic syndrome.
